The purpose of the study is to evaluate the efficacy and safety of tiragolumab plus atezolizumab compared with placebo plus atezolizumab in participants with previously untreated locally advanced, unresectable or metastatic PD-L1-selected non-small cell lung cancer (NSCLC), with no epidermal growth factor receptor (EGFR) mutation or anaplastic lymphoma kinase (ALK) translocation. Eligible participants will be randomized in a 1:1 ratio to receive either tiragolumab plus atezolizumab or placebo plus atezolizumab.
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Investigator-Assessed Progression-Free Survival (PFS) in the Primary Analysis Set
Timeframe: From randomization to the first occurrence of disease progression or death from any cause, whichever occurs first (up to approximately 59 months)
Overall Survival (OS) in the Primary Analysis Set
Timeframe: From randomization to death from any cause (up to approximately 59 months)
Percentage of Participants With Adverse Events (AEs)
Timeframe: Up to approximately 59 months
Percentage of Participants With Cytokine-Release Syndrome (CRS)
Timeframe: Up to approximately 59 months