Danish pregnant women are recommended ad daily vitamin D supplement of 10 µg. Despite the fact that 9 out of 10 women take vitamin D supplements, more than 40% of pregnant women are vitamin D deficient, putting them at an increased risk of pregnancy complications like fetal growth restriction and pre-eclampsia. Our hypothesis is that pregnant women would benefit from an increased intake og vitamin D and that an intake of 90µg/day can reduce the prevalence of placenta-related pregnancy complications. Combining a double-blinded randomized trial (10µg vs.90µg) with collection of placental material, we want to test if the prevalence of pregnancy complications is reduced and explore how vitamin D affects placenta to improve our understanding of the disease pathology and risk factors.
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The prevalence of pre-eclampsia (PE)
Timeframe: From 20 weeks of gestation to delivery
The prevalence of fetal growth retardation (FGR)
Timeframe: From 20 weeks of gestation to delivery
The prevalence of gestational diabetes (GDM)
Timeframe: From 20 weeks of gestation to delivery