The Prevalence of Nonalcoholic Fatty Liver Disease (NAFLD) Pediatric Patients (NCT04284371) | Clinical Trial Compass
TerminatedNot Applicable
The Prevalence of Nonalcoholic Fatty Liver Disease (NAFLD) Pediatric Patients
Stopped: lack of funding - no results to report
United States150 participantsStarted 2016-02-10
Plain-language summary
The prevalence of liver steatosis, steatohepatitis, fibrosis, and hemosiderosis in overweight and obese US Military dependent pediatric patients using MR Elastography and Quantitative MRI
Who can participate
Age range10 Years ā 17 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
ā. DEERS eligible patients from the San Antonio Military Medical Center Healthy Habits clinic and pediatric endocrine, pediatric gastroenterology, adolescent, and general pediatric clinics, as well as from Wilford Hall's pediatric clinic.
ā. Overweight (BMI \> 85% and \< (Control group) Normal BMI for age and gender (BMI \<85%) 95% for age and gender) or obese (BMI \>/= 95% for age and gender)
ā. 10 - 17 years old
ā. Cognitively able to understand and provide written informed assent
ā. Written informed consent from parent or legal guardian
Exclusion criteria
ā. Current or prior history of liver disease (to include chronic hepatitis B or C, hemochromatosis, Wilson's disease, autoimmune hepatitis, primary biliary cirrhosis, primary sclerosing cholangitis, HIV, biliary atresia, or Caroli/choledochal disease), or other known liver disease.
ā. Pregnancy (self-reported or through positive beta HCG test during study)
ā. Current use of hepatotoxic medications associated with liver disease/failure (antifungals, methotrexate, valproic acid)
ā. Carrying an implantable active medical device such as a pacemaker, vagal nerve stimulator, defibrillator, or non-MRI compatible cochlear implant.
ā. Previous claustrophobia/anxiety with MRI scanner or developmental delays that may result in failed MRI scan (e.g.autism, anxiety disorder)