Chordal Repair for Transcatheter Mitral Valve Repair (TMVr)

Inclusion Criteria: * Presence of moderate to severe Mitral regurgitation as read on an echocardiographic study performed within 60 days prior to procedure. * Estimated post-ePTFE chordae tendineae implantation coaptation surface is adequate in the judgment of the operating physician and the patient eligibility committee. * Degenerative mitral valve disease. * Patients who have been evaluated and no contraindication has been found for open heart surgery OR candidates for mitral valve surgery who, according to current guidelines, are at elevated surgical risk AND for whom transcatheter therapy is deemed more appropriate than open heart surgery in the judgement of the Site Heart Team. Exclusion Criteria: * Untreated clinically significant coronary artery disease requiring revascularization * Creatine Kinase-MB (CK-MB) obtained within prior 14 days \> local laboratory Upper Limit of Normal (ULN) * Age \<30/40 or \> 85 years * Presence of any of the following: * Estimated pulmonary artery systolic pressure (PASP) \> 70 mmHg assessed by site based on echocardiography or right heart catheterization * Hypertrophic cardiomyopathy, restrictive cardiomyopathy, constrictive pericarditis, ischemic or non-ischemic Functional mitral regurgitation or any other structural heart disease causing heart failure * Infiltrative cardiomyopathies (e.g., amyloidosis, hemochromatosis, sarcoidosis) * Hemodynamic instability requiring inotropic support or mechanical heart assistance * Hemodynamic ins…