CompletedPhase 2

Intralesional Vitamin D Injection for Treatment of Common Warts

United States77 participantsStarted 2020-10-20

Plain-language summary

Researchers are trying to find out if injecting Vitamin D into a wart is an effective treatment.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adult patients seen at the Mayo Clinic Rochester practices * Patients suffering from one or more cutaneous warts as diagnosed by the examining physician at baseline visit on typical diagnostic characteristics * Able to provide consent * Both recalcitrant and non-recalcitrant warts will be included Exclusion Criteria: * Patients with prior use of home or office-based destructive treatments for this wart(s) in the last 1 month with salicylic acid (SA) or cryotherapy * Immunoadjuvant therapy for warts in the last 4 months (e.g Candida) * History of vitamin D injection of warts ever * High-dose vitamin D supplementation (\>4,000 IU daily or equivalent) in the preceding 3 months * Pregnancy or lactation * Facial or genital warts * Lesions not felt by the examining clinician to be a wart (e.g., corns or calluses) * Immunosuppression (to include immunosuppressive medications or conditions as judged by the physician evaluating the patient at the baseline visit). * Allergy to sesame oil

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Complete Regression of Wart

Timeframe: 24 weeks

Trial details

NCT IDNCT04278573

SponsorStephen P. Merry

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-04-04

Results submitted2024-04-03

View on ClinicalTrials.gov More Warts trials

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.