UnknownNot Applicable

Determination of ALDH1b1 and ALDH2 Polymorphisms Frequency in the Brazilian Population

Brazil300 participantsStarted 2022-01-02

Plain-language summary

A case-control study with oral squamous cell carcinoma (OSCC) patients from Instituto do Câncer do Estado de São Paulo (ICESP) and healthy volunteers. In this study, it will be collected saliva samples from both groups that will be submitted to sequencing analysis to evaluate the frequency of ALDH1b1 and ALDH2 polymorphisms in the Brazilian population. Also, correlate OSCC risk to alcohol consumption or smoke, by applied questionnaires.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * OSCC diagnostic for case group * Able to read and sign the consent form. * Able for saliva collection. * Able to understand the applied questionnaires. Exclusion Criteria: * Unable to read and sign the consent form. * Unable for saliva collection. * Unable to understand the applied questionnaires. * OSCC patient's companions for healthy volunteers.

What they're measuring

Frequency of ALDH1b1 and ALDH2 polymorphisms

Timeframe: 1 year

Trial details

NCT IDNCT04270201

SponsorInstituto do Cancer do Estado de São Paulo

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2022-12-01

Contact for this trial

Isabela C de Souza

+5511982496744 isabelasouza@usp.br

View on ClinicalTrials.gov More Oral Squamous Cell Carcinoma (OSCC) trials