WorkWell: Work-based Activity and Metabolic Health (NCT04269070) | Clinical Trial Compass
CompletedNot Applicable
WorkWell: Work-based Activity and Metabolic Health
United States15 participantsStarted 2021-03-25
Plain-language summary
This study will test whether a range of pre-clinical cardiometabolic biomarkers can be improved via regular intervals of standing and light-intensity physical activity in real-world office environments.
Who can participate
Age range18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Women and men age 18 yrs and older
* Holds a job where primary work activities are done seated
* Has the space and ability to use a sit-to-stand workstation in their primary workspace
* Works in an office setting or remotely for ≥ 4 days per week
* Have a BMI ≥ 25.0 (≥23.0 for individuals of Asian descent)
Exclusion Criteria:
* Currently taking diabetes medication
* Taking any of the following medications or treatments:
* Medication to control high blood pressure
* Medication to treat high glucose
* Blood thinners
* Hormone replacement therapy (in the past 12 months)
* Corticosteroids
* High dose statins (Dr. Reaven, MD to adjudicate eligibility based on dosage)
* 2nd generation antipsychotics
* Current or previous foot or lower limb injuries
* Current use of sit-stand workstation
* Current smoker
* Neuromuscular or cardiovascular disorders or other serious active medical issues, including deep vein thrombosis or respiratory issues
* Has a physical impairment or musculoskeletal condition that will prevent the subject from standing or light-intensity walking for a maximum of 30 minutes
* Has been advised to avoid prolonged periods of sitting or standing by a physician or other healthcare provider
* History of inflammatory bowel or intestinal malabsorption conditions
* Use of prebiotics, probiotics or antibiotics in the last 3 months
* Serious food allergies or restrictions
* Participants who will be travelling 3 or more days out of their…
What they're measuring
1
Change in 2-hour postprandial area-under-the-curve blood glucose at 2 weeks