MitoQ for Fatigue in Multiple Sclerosis (MS)

Inclusion Criteria: * MS (any clinical subtype) as diagnosed by the 2017 McDonald criteria * EDSS score of 2 to 8 * complaint of fatigue that has been persistent for at least two months * Modified Fatigue Impact Scale (MFIS) score of 38 or greater Exclusion Criteria: * treatment with systemic glucocorticoids in the prior six weeks * Beck Depression Inventory (BDI) \>31 or BDI-FS\>10 (severe depression) * significant MS exacerbation in prior 30 days * previous use of MitoQ or Coenzyme Q10 (CoQ10) within thirty days of screening appointment * other significant health problem that might increase risk of patient experiencing Adverse Events (AEs), e.g.: * active coronary heart disease * liver disease * pulmonary disease * diabetes mellitus * pregnancy or intending to become pregnant or breastfeeding * unable to complete the self-report forms * unable to give informed consent * prisoners * any condition which would make the patient in the opinion of the investigator unsuitable for the study