Feasibility Study of the AffloVest in Bronchiectasis (NCT04266873) | Clinical Trial Compass
SuspendedNot Applicable
Feasibility Study of the AffloVest in Bronchiectasis
Stopped: Data analysis review of current data
United Kingdom30 participantsStarted 2020-02-01
Plain-language summary
Feasibility study of High Frequency Chest Wall Oscillation (HFCWO) using the AffloVest in 30 patients with Bronchiectasis over a 6 week period. Outcome measures include lung function, quality of life questionnaire, High resolution computed Tomography and visual analogue scale for ease of clearance.
Who can participate
Age range18 Years
SexALL
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Inclusion Criteria:
* Adult male and females 18 years or over
* Current diagnosis of bronchiectasis
* Productive of sputum on a daily basis
* Clinical stability over a 2 week period prior to enrolment
Exclusion Criteria:
* Cystic fibrosis
* Severe obstructive airways disease (defined as FEV1 less than 25 percent)
* Predominant lung disease is not bronchiectasis in the opinion of the investigator (e.g. asthma, Chronic Obstructive Pulmonary Disease (COPD), pulmonary fibrosis)
* Bronchiectasis in only 1 lobe
* Currently treated non-tuberculous mycobacterial lung disease
* Acute congestive cardiac failure
* Contra-indication or unable to perform HRCT imaging, including pregnancy
* Contra-indication to using AffloVest including lung malignancy, recent rib fractures, radiological evidence of lung cavitation, and recent significant haemoptysis (in the opinion of the investigator)
* History of poor adherence to physiotherapy treatment
* Cognitive or memory problems affecting ability to follow instructions or give informed consent