Antiangiogenic Therapy of Choroidal Neovascularisation Associated With Central Chorioretinitis (NCT04245072) | Clinical Trial Compass
UnknownNot Applicable
Antiangiogenic Therapy of Choroidal Neovascularisation Associated With Central Chorioretinitis
Ukraine100 participantsStarted 2018-03-27
Plain-language summary
The purpose of this study is to determine the effectiveness of antiangiogenic therapy to choroidal neovascularization secondary to central chorioretinitis.
Who can participate
Age range18 Years – 90 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Able to read (or, if unable to read due to visual impairment, be read to verbatim by the person administering the informed consent form or a family member) and understand the informed consent form and willing to sign the informed consent form.
* Signed informed consent form.
* Men and women ≥ 18 years of age.
* Willing, committed, and able to return for all clinic visits and complete all study-related procedures.
* First diagnosed active subfoveal or juxtafoveal (within 1 to 199 μm of the center of the fovea) CNV secondary to chorioretinitis as defined by leakage on FA
* Transparent optical media and possibility to mydriasis.
* Best corrected visual acuity at least 20/100 Equivalent of Snellen (ETDRS).
Exclusion Criteria:
* Ocular media of insufficient quality to obtain fundus and OCT images in the study eye
* Recurrent CNV in the study eye
* History or presence of CNV with an origin other than chorioretinitis in the study eye
* Ocular inflammation or external ocular inflammation in the study eye
* Concurrent disease in the study eye that would compromise BCVA or require medical or surgical intervention during the study period
* Any ocular disorder in the study eye that, in the opinion of the investigator, may confound interpretation of the study results
* Significant scarring or atrophy in the fovea that indicates substantial irreversible vision loss in the study eye
* Evidence at examination of infectious blepharitis, keratitis, scleritis, or conjun…
What they're measuring
1
Mean Change in Best Corrected Visual Acuity (BCVA) as Measured by ETDRS Chart
Timeframe: Baseline-Month 12
Trial details
NCT IDNCT04245072
SponsorThe Filatov Institute of Eye Diseases and Tissue Therapy