Active — Not RecruitingNot Applicable

Mechanisms of Prediabetic States in Sleep Apnea

United States300 participantsStarted 2019-11-26

Plain-language summary

The purpose of this study is to better understand how sleep apnea contributes to the development of diabetes.

Who can participate

Age range20 Years – 65 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Overweight or obese * Prediabetic * Sleep apnea Exclusion Criteria: * Diabetic * Severe hypertension * Taking medications that can confound assessments * Any history of known bleeding disorders * Any underlying disease likely to limit life span or increase risk of intervention * Currently pregnant, trying to get pregnant or nursing

What they're measuring

Plasma norepinephrine levels

Timeframe: Untreated, within 4 months of screening

Plasma norepinephrine levels

Timeframe: CPAP, within 4 months of screening

Plasma norepinephrine levels

Timeframe: Niacin, within 4 months of screening

Trial details

NCT IDNCT04234217

SponsorUniversity of Chicago

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-07-15

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