Pancreatic Islet Transplantation to the Anterior Chamber of the Eye

Inclusion Criteria: * T1D participants that fulfill criteria for islet transplantation * Systemic immunosuppression * At least one eye with VA from HM to 0.1, and fellow eye with equal or better VA * Age ≥ 18 years * Normal cornea with good visualization of the anterior segment * Participant not eligible or with no wish for standard pancreatic islet into the hepatic portal system or pancreas transplantation * Participants who have recently been involved in research or who are actively involved in research may be recruited at the discretion of the chief investigator if the active research has no impact on glucose self-management. Exclusion Criteria: * VA below HM or above 0.1 * Neovascular glaucoma * Iris neovascularization * Ongoing treatment with intraocular anti-VEGF or steroids (and no injection within 4 weeks) in the study eye and no anticipated need for therapy during study period. * Ongoing retinal laser photocoagulation * Signs of current infection or inflammation * Intraocular surgery within 3 months * Previous or planned anterior segment surgery for glaucoma * Poor visualization of the anterior chamber