Skin bioMARkers for Atopic Eczema Therapy Evaluation

Inclusion Criteria: * Volunteers with AD defined according to the UK working party diagnostic criteria * Male or female aged 18-65 years old at baseline (Visit 1) * Volunteer understands the purpose, modalities and potential risk of the trial * Participants able to read and understand English * Participants willing to sign the informed consent Exclusion Criteria: * Participants with a known allergy/hypersensitivity to any of the excipients of the trial preparations. * Participants with acne, suntan, birth marks, multiple nevi, tattoos, blemishes or dense body hair that obstruct the test areas. * Investigator assessment of eczema severity at the treatment (anatomical) sites is almost clear or greater (score ≥1) based on the Investigators static global assessment scale at screening and baseline. At the start of the study the skin of the test sites (forearms) will therefore be clear (0) of the signs of eczema * Participants with a condition that in the opinion of the investigator contradicts participation in the study. * Pregnant female participants; breastfeeding female participants; and female participants of childbearing potential who are unwilling or unable to use a highly effective method of contraception as outlined in this protocol for the duration of the study and for at least 28 days after the last dose of investigational product. * Use of any topical product on the test areas within 7 days prior to Baseline/Day 1, including cosmetic moisturizers and sunscreen. Parti…