CompletedNot Applicable

Effects of Red Blood Cells Transfusion on Renal Blood Flow

Italy33 participantsStarted 2020-03-01

Plain-language summary

The renal Doppler resistive index (RRI) is a noninvasive tool that has been used to assess renal perfusion in the intensive care unit (ICU) setting. It is associated with the occurrence of acute kidney injury (AKI). Many parameters have been described as influential on the values of renal RI. Red blood cell (RBC) transfusion were shown to be able to increase renal oxygenation in animal model, whereas crystalloid resuscitation did not. We sought to describe the different effect of crystalloids infusion and RBC transfusion on renal blood flow, as evaluated with doppler ultrasound

Who can participate

Age range18 Years – 90 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age \> 18 and \< 90 * Hemoglobin ≥7 and ≤ 10 g/dl Exclusion Criteria: * Ultrasound RRI evaluation non available * Patients with arrhythmia * Pregnancy * Refusal to give consent * History of renal transplantation * Central venous access in superior vena cava not available Critical active bleeding

What they're measuring

Change in renal resistivity index (RRI) after intervention

Timeframe: after 60 minute from intervention

Change Renal Venous Stasis Index (RSVI) after intervention

Timeframe: after 60 minute from intervention

Trial details

NCT IDNCT04194047

SponsorUniversità degli Studi di Ferrara

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2022-09-01

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