WithdrawnNot Applicable

Sleep Apnoea Syndrome and Hepatocellular Carcinoma

Stopped: the possibility of obtaining histological data is too low due to the lack of availability of biological samples

France0Started 2020-01-21

Plain-language summary

Obstructive sleep apnea (OSA), one of the most frequent respiratory diseases, could represent a major worsening factor in a non alcoholic steatohepatitis and neoplastic context. Our hypothesis is that OSA promotes the prevalence of HCC related to NASH. This national, multicenter study aims to compare the prevalence of OSA in a group of patient curatively resected for NASH-related HCC with a group of HCV-related HCC.

Who can participate

Age range18 Years

SexALL

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Inclusion Criteria: * Man and woman * \>18 years * Diagnosis of NASH-induced HCC or HCV-induced HCC * Patients treated by surgical excision * Patients not opposed to the study Exclusion Criteria: * Patient refusal * Alcohol consumption\> 20g / day for women and\> 30g / day for men * Patient with HCV genotype 3 * Tumor vascular invasion identified preoperatively * Other etiologies of hepatopathies (alcoholic, viral B, autoimmune, hemochromatosis) * Other chronic respiratory diseases: chronic obstructive pulmonary disease, respiratory insufficiency * Patient weight variation \>5% since surgical treatment of his HCC * Subject deprived of liberty or under guardianship

What they're measuring

The study will compare OSA prevalence in a group of patient curatively resected for NASH-related HCC with a group of HCV-related HCC.

Timeframe: 2 years

Trial details

NCT IDNCT04190498

SponsorUniversity Hospital, Grenoble

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2021-04-12

View on ClinicalTrials.gov More Sleep Apnea, Obstructive trials