Topical Pentoxifylline Gel on Behcet's Disease Genital Ulcers

Inclusion Criteria: * Meets the International Study Group criteria for Behcet's Disease (BD) * Presents with at least one active genital lesion accessible to measurement * Adult (\>18 years) male or a non-pregnant, non-lactating female * Has signed an IRB approved subject consent form * Has completed all screening procedures satisfactorily, is deemed to be an acceptable subject and is otherwise eligible for entry into the study * Is willing and able to comply with the protocol * Subject's treating physician confirm that the subject has previously had a genital ulcer due to Behcet's Disease Exclusion Criteria: * Has a severe, acute, or chronic systemic disease other than BD such as congestive heart failure, hepatic failure, renal failure, systemic lupus erythematosus, Stevens- Johnson syndrome, ulcerative colitis, cancer, leukemia, diabetes, AIDS, or any other condition for which they are immune-compromised * Has received PTX in any form over the previous 5 days prior to enrollment * Has a history of, or is currently exhibiting, any disease or condition, which, in the opinion of the principal investigator, would place the subject at increased risk during study therapy * Has experienced recent cerebral and/or retinal hemorrhage or in patients who have previously exhibited intolerance to this product or methylxanthines such as caffeine, theophylline, and theobromine * Is receiving apremilast or anti-TNF agents such as; Rituximab, Infliximab, Adalimumab, Etanercept (azathiopri…