Nasal Inhalation of Isopropyl Alcohol for the Treatment of Nausea in Patients With Cancer (NCT04181463) | Clinical Trial Compass
Not Yet RecruitingPhase 2
Nasal Inhalation of Isopropyl Alcohol for the Treatment of Nausea in Patients With Cancer
United States112 participantsStarted 2026-11-05
Plain-language summary
The goal of this research study is to understand the effect of inhalation approaches in reducing nausea in cancer patients.
Who can participate
Age range18 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Rate current severity of acute/chronic nausea \>= 4 on NRS (Numeric Rating Scale)
* Diagnosis of cancer
* Able to read/write in English
* Referred to supportive care service as an inpatient or outpatient
* Rate anxiety as =\< 4 on ESAS-FS (Edmonton Symptom Assessment Scale-Financial Distress and Spiritual Pain)
* Participants must agree to inhale isopropyl alcohol
Exclusion Criteria:
* Received anti-emetics in the last 30 minutes
* Received medical procedures (e.g. blood draws) which required exposure of isopropyl alcohol in the last 30 minutes
* Inability to inhale through nares (including recent upper respiratory infection)
* Known allergy to isopropyl alcohol
* Delirium (i.e., score \>= 7 on the Memorial Delirium Assessment Scale \[MDAS\])
* Have never been on anti-emetics during the course of the treatment here (anti-emetic naive)
What they're measuring
1
Change in nausea
Timeframe: Baseline up to 5 minutes post-intervention