Skin Microbial Ecology in Atopic Dermatitis

Inclusion Criteria: * ≥13 to 65 years of age (inclusive) for PS, ≥13 for AD and NA, male or female * Optional Bx sub study - only adults (18-65 yrs; inclusive only) * Able to understand protocol and give consent * Able to keep clinic/study appointments and comply with study related procedures * Must be able to read, speak, and understand English * Chronic AD, according to the American Academy of Dermatology (AAD) Consensus Criteria (Eichenfield 2014), that has been present for at least 1 year before the enrollment visit * Chronic PS, according to the AAD Consensus Criteria (Menter et al 2008 (section 1)), that has been present for at least 1 year before the enrollment visit. * AD subjects: have active lesions on upper extremities, lower extremities, or trunk and a total disease severity of high moderate-to-severe (EASI ≥12) * PS subjects: have active lesions on upper extremities, lower extremities, or trunk and a total disease severity of high moderate-to-severe (PASI ≥7) Exclusion Criteria: * Unwilling and/or unable to complete informed consent process * \<13 or \> 65 years of age for PS, \>13 for AD and NA * AD subjects: disease without upper extremity, lower extremity, or trunk lesions * AD subjects: total disease severity less than moderate (EASI \<12), depending on enrollment * PS subjects: disease without upper extremity, lower extremity, or trunk lesions * PS subjects: total disease severity less than moderate (PASI \<7), depending on enrollment * Control subjects: …