A Study to Evaluate Lumasiran in Patients With Advanced Primary Hyperoxaluria Type 1

Inclusion Criteria: * Has documented diagnosis of primary hyperoxaluria type 1 (PH1) * Estimated glomerular filtration rate (eGFR) ≤45 mL/min/1.73 m\^2 for patients ≥12 months of age (\<12 months of age, must have serum creatinine considered elevated for age) * Meets plasma oxalate level requirements * If taking Vitamin B6 (pyridoxine), must have been on stable regimen for at least 90 days * If on dialysis, may be on hemodialysis therapy only and must have been on a stable regimen for at least 4 weeks Exclusion Criteria: * Hemodialysis/peritoneal dialysis combination therapy or peritoneal dialysis alone * Diagnosis of conditions other than PH1 contributing to renal insufficiency * History of liver transplant * History of kidney transplant and currently receiving immunosuppressants