Effects of Overnight Low Oxygen Exposure on Energy Balance

Inclusion Criteria: * Men and women aged 20 - 45 years * Body mass index between 18.5 - 24.5 kg/m2 * Born at altitudes less than 2,100 meters (\~7,000 feet) * Currently residing in Tallahassee, Florida or the surrounding area * Not taking any medication(s) that interfere with metabolism or oxygen delivery/transport for four weeks before and throughout the entire study (e.g., includes sedatives, sleeping aids, tranquilizers, and/or any medication that depresses ventilation, diuretics, alpha, and beta-blockers). * Willing to refrain from smoking, vaping, chewing tobacco, and dietary supplement use throughout the entire study * Willing to spend two overnight visits on the Florida State University campus. Exclusion Criteria: * Living in areas that are more than 1,200 m (\~4,000 feet), or have traveled to areas that are more than 1,200 m for five days or more within the last two months * Metabolic or cardiovascular abnormalities, gastrointestinal disorders, or any condition that interferes with metabolism or oxygen delivery/transport (e.g., kidney disease, diabetes, cardiovascular disease, etc.) * Prior diagnosis of apnea or other sleeping disorders * Prior diagnosis of high-altitude pulmonary edema or high-altitude cerebral edema * Prior diagnosis of anemia or sickle cell anemia/trait * Present condition of alcoholism, anabolic steroid, or other substance abuse issues * Women who are pregnant, lactating, planning to become pregnant, or who have had an irregular menstrual cycle…