CompletedPhase 4

Nasal Decolonization for Orthopedic Trauma Patients

United States65 participantsStarted 2020-02-19

Plain-language summary

Many surgical site infections are caused by bacteria that is transferred from a patient's nose to their open surgical wound. Some small studies have shown that putting povidone-iodine in a patient's nose reduces this risk. This study aims to evaluate the real-world effectiveness of nasal povidone-iodine (PROFEND®) in a group of 50 patients at the University of Iowa.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients undergoing operative fixation of lower extremity fractures at the University of Iowa during the study period. Exclusion Criteria: * Patients unable to provide informed consent due to head trauma or dementia.

What they're measuring

Number of Participants With Staphylococcus Aureus Nasal Colonization

Timeframe: Within 6 hours after first dose of povidone-iodine

Trial details

NCT IDNCT04146116

SponsorUniversity of Iowa

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-06-08

Results submitted2022-11-15

View on ClinicalTrials.gov More Surgical Site Infection trials