UnknownNot Applicable

Labor Induction With Misoprostol Versus Oxytocin in Women With Premature Rupture of Membranes

Israel200 participantsStarted 2019-12-01

Plain-language summary

This study compares the rate of vaginal delivery after induction of labor with misoprostol versus oxytocin in women with prelabor rupture of membranes. Participants will be randomized to receive either oral misoprotsol every four hours until going into labor, or intravenous oxytocin in increasing dose.

Who can participate

Age range18 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Women in their 1st - 4th delivery * Term prelabor rupture of membranes (37+0 to 42+0 gestational age) * Vertex presentation * Singleton pregnancy Exclusion Criteria: * Multiple pregnancy * Previous cesarean section * Chorioamnionitis on admission * \>2 symptomatic uterine contractions in 10 minutes * Prostaglandins hypersensitivity * Contraindication for vaginal delivery

What they're measuring

Vaginal delivery rate

Timeframe: During delivery

Trial details

NCT IDNCT04143685

Sponsorsammour.rami

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2021-08-01

View on ClinicalTrials.gov More Prelabor Rupture of Membranes trials