CompletedNot Applicable

Treatment of Papillary Thyroid Carcinoma With Radiofrequency Ablation

United States5 participantsStarted 2020-06-15

Plain-language summary

Investigators intend to evaluate the efficiency of Radiofrequency ablation (RFA) therapy to treat papillary thyroid carcinoma.

Who can participate

Age range

18 Years – 85 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Are adults * Nodule with Papillary thyroid carcinoma meeting the below criteria: * Diagnosed by fine needle aspiration (FNA) cytology. * Size \< 1.5 cm * Non-surgical therapy is considered acceptable by the treating physician * Radiology evaluation deems the lesion amenable to RFA therapy with minimal risk of complication Exclusion Criteria: * Clinical evidence for a multifocal papillary thyroid malignancy * Clinical evidence for local or distant metastatic disease * Pregnancy * Vocal cord paralysis on contralateral side * Coagulopathy or patients on anticoagulation therapy * Patients with prior neck surgery or neck radiation * Patients with neck anatomy that precludes easy access by RFA * Patients with comorbidities deemed too high of a risk for general anesthesia * Treatment with another investigational drug or intervention (within 6 weeks of planned RFA). * Current drug or alcohol use or dependence that, in the opinion of the site investigator, would interfere with adherence to study requirements.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Changes in Thyroid Nodule Size

Timeframe: 24 months

Trial details

NCT IDNCT04129411

SponsorMayo Clinic

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-05-07

Results submitted2025-04-14

View on ClinicalTrials.gov More Papillary Thyroid Cancer trials

Who can participate

Age range

18 Years – 85 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.