Treatment of Papillary Thyroid Carcinoma With Radiofrequency Ablation

Inclusion Criteria: * Are adults * Nodule with Papillary thyroid carcinoma meeting the below criteria: * Diagnosed by fine needle aspiration (FNA) cytology. * Size \< 1.5 cm * Non-surgical therapy is considered acceptable by the treating physician * Radiology evaluation deems the lesion amenable to RFA therapy with minimal risk of complication Exclusion Criteria: * Clinical evidence for a multifocal papillary thyroid malignancy * Clinical evidence for local or distant metastatic disease * Pregnancy * Vocal cord paralysis on contralateral side * Coagulopathy or patients on anticoagulation therapy * Patients with prior neck surgery or neck radiation * Patients with neck anatomy that precludes easy access by RFA * Patients with comorbidities deemed too high of a risk for general anesthesia * Treatment with another investigational drug or intervention (within 6 weeks of planned RFA). * Current drug or alcohol use or dependence that, in the opinion of the site investigator, would interfere with adherence to study requirements.