Treatment of Anastomotic Leakage After Rectal Cancer Resection (NCT04127734) | Clinical Trial Compass
UnknownNot Applicable
Treatment of Anastomotic Leakage After Rectal Cancer Resection
1,246 participantsStarted 2020-04-01
Plain-language summary
The TENTACLE: Rectum study is a multinational retrospective cohort study that includes patients with anastomotic leakage after rectal cancer resection.
The study aims to develop an anastomotic leakage severity score and to evaluate the efficacy of different treatments of anastomotic leakage.
Who can participate
Age range18 Years
SexALL
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Inclusion Criteria:
* Aged 18 years or older;
* Cancer located in the rectum, defined according to the international definition of the rectum consensus \[D'Souza 2019\];
* Rectal cancer resection with primary anastomosis (with or without diverting loop ileostomy) for either primary cancer, completion after local excision or salvage resection for regrowth after watch \& wait or local excision;
* Postoperative anastomotic leakage according to the following definition: "a breach in a surgical join between two hollow viscera, with or without active leak of luminal contents" \[Peel 1991\].
Exclusion Criteria:
* Rectal resection for benign disease;
* Rectal resection for recurrent rectal cancer after previous low anterior resection or other primary malignancies;
* Multivisceral resection (lateral lymph node dissection can be included)
* Emergency resection;