Trial to Evaluate Safety, Tolerability, Efficacy of PerioSept® as Adjunct to SRP in Subjects With Periodontitis

Inclusion Criteria: * Subjects male or female 18 to 80 years of age, inclusive. * Subjects must be diagnosed with moderate to severe generalized periodontitis (ADA Classification Case Type III or IV) as determined by the investigator. * Subjects must have at least 4 qualifying target teeth (having a dental pocket with PPD ≥ 6mm and BOP) (teeth having no endodontic disease - treated or untreated). * Subjects must have at least 12 teeth in the functional dentition, excluding second and third molars In subjects with limited dentition, tooth loss should not be due to traumatic occlusion * Females of childbearing potential must agree to use of birth control (hormonal, barrier method or abstinence). Hormonal contraceptives must have started not fewer than 30-days before baseline visit/Day 1. * Subjects must sign informed consent document(s) prior to initiation of any study-specific procedures and treatments. * Subjects who are able and willing to adhere to the study visit schedule and other protocol requirements. Exclusion Criteria: * History of and/or known risk of life-threatening anaphylactic reactions to taurolidine, any of the components in the investigational drug product. * Presence of an acute periodontal abscess. * Subjects with healing disorders (e.g. uncontrolled diabetes mellitus, oral cancer) that could compromise wound healing and/or preclude periodontal surgery. * Subjects who are taking medications that compromise wound healing presenting with clinical evidence o…