Evaluation of the Safety and Immunogenicity of Simultaneously Administration of EV71 Vaccine and Influenza Vaccine

Inclusion Criteria: * subjects aged from 6-11 months old at the date of recruitment; * with informed consent signed by parent(s) or guardians; * parent(s) or guardians are able to attend all planned clinical appointments and comply with all study instructions; * subjects not receive any vaccination within 14 days at the date of recruitment; * subjects have not been vaccinated with EV71 vaccine, seasonal flu vaccine; * subjects with no medical history of EV71 infection; * axillary temperature ≤37.0℃ Exclusion Criteria: * subject who has a medical history with Hypersensitiveness, eclampsia, epilepsy, cerebropathia and neurological illness; * allergic to any ingredient of vaccine or with allergy history to any vaccine; * subjects with immunodeficency or suspected impairment of immunologic function (e.g. caused by HIV), or subjects are in the process of immunosuppressor therapy(Taking orally injecting of steroid hormone); * administration of immunoglobulins within 30 days prior to this study; * acute febrile disease(temperature ≥ 37.0°C) or infectious disease; * have a clearly diagnosed history of thrombocytopenia or other coagulopathy, * may cause contraindications for subcutaneous injection; * any serious chronic illness, acute infectious diseases, or respiratory diseases; * severe cardiovascular disease, liver and kidney diseases or diabetes mellitus with complications; * any kind of infectious, purulent, or allergic skin diseases; * any other factor that makes the investig…