This project intends to provide important, previously unmet answers regarding biological associations with myopia (nearsightedness) progression in order to improve the ability to predict patients who are most likely to benefit from myopia control, as well as questions frequently posed by patients and practitioners about the side effects, mechanism, and discontinuation of soft bifocal contact lens myopia control. The first three aims examine the association between biological variables that can be measured non-invasively and myopia progression, and they will be conducted regardless of the outcome of the currently in progress BLINK Study. The last three specific aims will be conducted if soft bifocal contact lenses slowed myopia progression by 30% or more in the BLINK Study, and they can be investigated with very few additional measurements.
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The Statistical Correlation Between Three-year Change in Choroidal Thickness and Three-year Change in Axial Length
Timeframe: Three years
The Statistical Correlation Between iPRGC Activity at BLINK2 Baseline and Three-year Change in Axial Length
Timeframe: Three years
The Statistical Correlation Between Light Levels Measured at Baseline and Three-year Change in Axial Length
Timeframe: Three years
Three-year Choroidal Thickness Change
Timeframe: 3 years
Duration of Exposure to Light Levels Exceeding 1000 Lux at Baseline
Timeframe: Baseline
Baseline iPRGC Activity
Timeframe: Baseline