CompletedNot Applicable

Relationship Between the VEGF Gene Polymorphism and Cardiometabolic Risk Factors

Poland400 participantsStarted 2018-01-01

Plain-language summary

The aim of the study is to determine the relationship between VEGF gene expression, VEGF gene polymorphism and serum leptin concentration in the Polish population in people with excessive body weight. In addition, the aim of the study is to look for relationships between the VEGF gene polymorphism and anthropometric and biochemical factors of cardiovascular risk and endothelial dysfunction such as body weight, waist circumference, serum total cholesterol, LDL, HDL, triglycerides, glucose and the occurrence of cardiovascular diseases in the family of a patient with excessive body weight in the Polish population.

Who can participate

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * informed consent in writing * stable body mass (+/- 1 kg) * excessive body mass (BMI ≥ 25 kg/m2- study group) * proper body mass (BMI \< 25 kg/m2- control group) Exclusion Criteria: * age \<18 years * secondary obesity * pregnancy, lactation * other conditions that in the opinion of researchers may pose any risk to the patient during the study.

What they're measuring

VEGF gene expression

Timeframe: through study completion, an average of 1 year

VEGF gene polymorphism

Timeframe: through study completion, an average of 1 year

serum leptin concentration

Timeframe: through study completion, an average of 1 year

Trial details

NCT IDNCT04077554

SponsorPoznan University of Medical Sciences

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2018-01-01

View on ClinicalTrials.gov More Polymorphism, Restriction Fragment Length trials