UnknownNot Applicable

STereotactic RadioAblation by Multimodal Imaging for VT (STRA-MI-VT)

Italy20 participantsStarted 2019-09-13

Plain-language summary

Study of multimodal-imaging guided stereotactic body radiotherapy (SBRT) for ventricular tachycardia (VT) ablation.

Who can participate

Age range

50 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * ICD/S-ICD recipients with refractory VT * Not eligible for conventional catheter ablation or -in alternative- that have undergone failing conventional catheter ablation attempts, refusing surgery for the treatment of the arrhythmia. * LVEF ≥ 20%. * Age ≥ 50 years. * Signed an IRB approved written informed consent document. Exclusion Criteria: * Previous radiotherapy with cardiac involvement. * Pregnancy or breastfeeding. * Active myocardial ischemia. * Acute revascularation in the past 120 days. * Acute hemodynamic instability (cardiogenic shock/NYHA IV). * Serious disease with presumed life expectancy less than 12 months. * Any condition that is deemed a contraindication in the judgment of the investigators.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

SBRT safety during 12 month follow-up

Timeframe: 12 months

SBRT efficacy based on reduction of VT episodes during 12 month follow-up

Timeframe: 12 months

Trial details

NCT IDNCT04066517

SponsorCentro Cardiologico Monzino

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-06-13

Contact for this trial

Corrado Carbucicchio, MD

+39 02 58001626 corrado.carbucicchio@ccfm.it

View on ClinicalTrials.gov More Refractory Ventricular Tachycardia trials

Who can participate

Age range

50 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.