Assessment of Exhaled Breath Condensate Hydrogen Peroxide (EBC H2O2) as Measured Using a New Devi… (NCT04061356) | Clinical Trial Compass
CompletedNot Applicable
Assessment of Exhaled Breath Condensate Hydrogen Peroxide (EBC H2O2) as Measured Using a New Device (Inflammacheckâ„¢) in Patients With Interstitial Lung Disease, Lung Cancer and Healthy Volunteers.
United Kingdom37 participantsStarted 2018-10-30
Plain-language summary
A cross-sectional study of EBC H2O2 levels, as measured by a novel device, 'Inflammacheckâ„¢', and other markers of disease severity in patients with ILD and Lung Cancer.
Who can participate
Age range18 Years
SexALL
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Inclusion Criteria:
* Male or Female, aged ≥18 years.
* A confirmed, clinician made diagnosis of Interstitial Lung Disease (ILD) supported by evidence of ILD on a CT chest scan recorded at any time.
* OR a clinician suspected or confirmed Lung Cancer, with or without asthma and/or COPD
* OR a healthy volunteer with no known history of lung disease (defined as no current clinical diagnosis of, or be receiving treatment for, a lung disease).
* Willing and able to give informed consent for participation in the study.
Exclusion Criteria:
* Existing co-morbidities that may prevent them from performing spirometry or other study measurements (at the discretion of the clinical investigator).
* Known other lung, chest wall, neuromuscular, or cardiac disease or abnormality (including end-stage disease or cancer) that would confound symptom scores and spirometry.
* In the opinion of the clinical investigator, participant could be put at risk of harm by having to perform any of the study procedures.
* Unable to comprehend the study and provide informed consent, e.g. insufficient command of English in the absence of someone to adequately interpret.
What they're measuring
1
Level of exhaled breath condensate hydrogen peroxide (EBC H2O2)