Post-menopausal women aged 40-65 with symptomatic hand osteoarthritis are invited to take part in this feasibility study. The study's aim is to investigate whether it is acceptable to women with painful hand OA to take an estrogen-containing therapy, and what is the best way of collecting some of the information in order to facilitate planning a full size trial. The investigator's long-term aim is to find out whether giving estrogen-containing therapy to women after the menopause improves hand OA symptoms.
Age range
40 Years – 65 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Feasibility: Rates of eligible participant identification, rates of recruitment/randomisation from different sources, retention rates
Timeframe: From the date of recruitment opening until the date of recruitment closing, 1 year
Feasibility: Frequency of adverse events related to the active study medication
Timeframe: Through study completion, 7 months
Feasibility: Bang's Blinding Index (likelihood of unblinding)
Timeframe: Week 24
Feasibility: Monitoring study medication compliance (via diaries)
Timeframe: From randomisation to end of treatment at Week 24