These studies are designed to assess the synergistic efficacy of topical 0.1% triamcinolone cream paired with 40,000 IU of oral vitamin D3 daily in treating mild to moderate psoriasis. The study is designed to have all subjects treated with triamcinolone cream (TAC) for 4 weeks, then will be randomized 1:1 into vitamin D3 or placebo for an additional 12 weeks. At that time, the study will become open-label and all subjects will be placed on (or continue) vitamin D3 for an additional 12 weeks. The study will take place over 28 weeks total.
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Improvement in Psoriasis Area and Severity Score (PASI) from baseline
Timeframe: Week 28
Improvement in Investigator Grade Assessment (IGA) from baseline
Timeframe: Week 28
Improvement in Body Surface Area (BSA) from baseline
Timeframe: Week 28
Manager, Clinical Research Operations