Nerve Transfer After Spinal Cord Injury- Multi-center (NCT04023591) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Nerve Transfer After Spinal Cord Injury- Multi-center
United States, Canada70 participantsStarted 2020-04-13
Plain-language summary
Current treatment strategies of acute cervical spinal cord injuries remain limited. Treatment options that provide meaningful improvements in patient quality of like and long-term functional independence will provide a significant public health impact. Specific aim: Measure the efficacy of nerve transfer surgery in the treatment of patients with complete spinal cord injuries with no hand function. Optimize the efficiency of nerve transfer surgery by evaluating patient outcomes in relation to patient selection and quality of life and functional independence.
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Age 18-65, inclusive
. At least 3 months of non-operative rehab therapy
. Mentally and physically willing and able to comply with evaluations
. Less than 36 months post-injury
. Stable ASIA scores with no evidence of functional improvement in motor or sensory examination for at least 3 months
. ASIA A or B determined by the International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)
. EMG/NCS verifies intact innervation (normal CMAPs) to the paralyzed target muscles below the level of injury
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is measuring hand and arm strength using Manual Motor Testing and handheld dynamometry — can you explain what those tests involve and what kind of muscle recovery they're actually looking for in participants?
2Since this trial is listed as 'active not recruiting,' does that mean enrollment is closed, and if so, are there similar nerve transfer surgery studies or programs that might still be open to someone in my situation?
3Nerve transfer surgery for spinal cord injury sounds very different from standard rehabilitation — can you walk me through what this procedure actually involves, what the recovery looks like, and how it compares to the rehab options already available to me?
4Because this study is listed as Phase NA, which often applies to surgical or procedural trials rather than drug trials, what does that mean for how much is already known about the safety and effectiveness of nerve transfer surgery for tetraplegia?
5Given that this is a multi-center trial measuring motor function outcomes, would my current level of injury and how long ago it happened affect whether nerve transfer surgery would even be worth exploring for me?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.