Acceptance of Clarithromycin in a Straw Compared to Syrup in Children With Upper Respiratory Tract Infections

Inclusion Criteria: * Male and female children weighing 12-40 kg. * Age 2 -12 years. * Written informed consent (parents). * Diagnosis of acute otitis media, tonsillitis, pharyngitis, or acute bacterial bronchitis requiring antibiotic treatment. Exclusion Criteria: * Participation in another study of investigational products or of devices parallel to, or less than 4 weeks before study entry, or previous participation in this study (for safety reasons). * Known to or suspected of not being able to comply with the study protocol and the use of clarithromycin. * Requirement for, or current use of, systemic antibacterial agents not specified in the protocol. * Necessity of dose reduction due to any concomitant disease. * Known human immunodeficiency virus (HIV) positive. * Other inflammatory/infectious diseases of the ear, the upper respiratory tract or the nose and throat. * History or presence of disease or concomitant medication contraindicating the use of clarithromycin. * Known or suspected intolerance / hypersensitivity to macrolides. * Contraindications according to the clarithromycin Summary of Product Characteristics (SmPC). * Indication for antibiotic treatment for less than 7 days or more than 10 days. * If known before entry, bacterial isolate resistant to clarithromycin.