A Trial to Assess the Safety, Immunogenicity and Efficacy of a Trivalent Rotavirus P2-VP8 Subunit Vaccine in Prevention of Severe Rotavirus Gastroenteritis in Healthy Infants in Africa and India

Inclusion Criteria: * Healthy infants as established by medical history and clinical examination before entering the study * Age: ≥6 and \<8 weeks at the time of first study vaccination (42 days through 55 days old, inclusive, with the day after birth considered 1-day old) * Parental/legal guardian's ability and willingness to provide written informed consent * Intention of the participants' parents to remain in the area with the child during the study period Exclusion Criteria: * Acute disease at the time of first study vaccination - temporary exclusion * Presence of fever on the day of first study vaccination (axillary temperature \>37.6oC) - temporary exclusion * Concurrent participation in another clinical trial throughout the entire timeframe for this study (participation in non-interventional observational study is allowed if there is no blood draw) * Presence of severe malnutrition (weight-for-height z-score ≤-3SD median, per WHO published child growth standards) or any systemic disorder (cardiovascular, pulmonary, hepatic, renal, gastrointestinal, hematological, endocrine, immunological, dermatological, neurological, cancer or autoimmune disease) as determined by medical history and/or physical examination that would compromise the participant's health or is likely to result in nonconformance to the protocol * History of premature birth (\<37 weeks gestation) and/or birth weight of \<2.5 kg * History of congenital abdominal disorders, intussusception, or abdominal …