The purpose of this study is to evaluate the reactogenicity, safety and immunogenicity of 2 doses of PED-HZ/su, GSK's vaccine candidate for the prevention of Herpes Zoster (HZ) in immunocompromised paediatric renal transplant recipients aged 1-17 years
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Number of subjects from the interventional groups, with solicited local adverse events (AEs)
Timeframe: Within 7 days after each vaccination (vaccines administered on day 1 and month 1)
Number of subjects from the interventional groups, with solicited general AEs
Timeframe: Within 7 days after each vaccination (vaccines administered on day 1 and month 1)
Number of subjects from the control groups with solicited general symptoms
Timeframe: Within 7 days after Visit Day 1
Number of subjects from the control groups with solicited general symptoms
Timeframe: Within 7 days after Visit Month 1
Number of subjects from the interventional groups with unsolicited AEs after each vaccination
Timeframe: Within 30 days after each vaccination (vaccines administered on day 1 and month 1)
Number of subjects from the control groups with unsolicited symptoms
Timeframe: Within 30 days after Visit Day 1
Number of subjects from the control groups with unsolicited symptoms
Timeframe: Within 30 days after Visit Month 1
Number of subjects with serious adverse events (SAEs), potential immune mediated diseases (pIMDs) and biopsy confirmed renal allograft rejection.
Timeframe: From Visit Day 1 up to Visit Month 2
Number of subjects from the interventional groups with seizures
Timeframe: Within 30 days after each vaccination (vaccines administered on day 1 and month 1)
Number of subjects from the non-interventional groups with seizures
Timeframe: Within 30 days after Visit Day 1
Number of subjects from the non-interventional groups with seizures
Timeframe: Within 30 days after Visit Month 1
Number of subjects from the interventional groups with generalized convulsive seizures
Timeframe: Within 7 days after each vaccination (vaccines administered on day 1 and month 1)
Number of subjects from the non-interventional groups with generalized convulsive seizures
Timeframe: Within 7 days after Visit Day 1
Number of subjects from the non-interventional groups with generalized convulsive seizures
Timeframe: Within 7 days after Visit Month 1
Percentage of subjects with Anti-gE antibody concentrations in terms of Geometric Mean Concentrations (GMCs)
Timeframe: At Month 2 (one-month post-dose 2)