Stopped: Preliminary analysis revealed no difference
Trigger finger is a common cause of hand pain and dysfunction. Its due to chronic inflammation of the flexor tendon that leads to a pulley system mismatch. Historically it has been managed either conservatively with corticosteroid injections or through a surgical release of the A1 pulley. Several corticosteroids have been used for injection- dexamethasone, methylprednisolone, triamcinolone, betamethasone, paramethasone, etc. The purpose of out study is to determine if a 0.5 cc injection of Triamcinolone 40 mg/mL will be the most effective steroid injection for the non-surgical treatment. Approximately 200 subjects will be enrolled and randomized to one of three treatment arms: Triamcinolone 40mg/mL, Triamcinolone 10mg/mL and Soluble dexamethasone 4mg/mL. Treatment success will be defined as lack of conversion to surgical treatment, or no desire to proceed with surgery during study period (3 months).
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Disabilities of the Arm, Shoulder and Hand (DASH)
Timeframe: 6 Weeks
Disabilities of the Arm, Shoulder and Hand (DASH)
Timeframe: 12 Weeks
Disabilities of the Arm, Shoulder and Hand (DASH)
Timeframe: 6 Month
Pain Visual Analog Score (VAS)
Timeframe: 6 Weeks
Pain Visual Analog Score (VAS)
Timeframe: 12 Weeks
Pain Visual Analog Score (VAS)
Timeframe: 6 Month
Patient Reported Outcomes Measurement Information System (PROMIS) Upper Extremity Scores
Timeframe: 6 Weeks
Patient Reported Outcomes Measurement Information System (PROMIS) Upper Extremity Scores
Timeframe: 12 Weeks
Patient Reported Outcomes Measurement Information System (PROMIS) Upper Extremity Scores
Timeframe: 6 Month