The Effects of a Novel Probiotic Supplement on Menopausal Symptoms and Bone Health

Inclusion Criteria: * Healthy post-menopausal woman * Last menstrual period has occurred at least 12 months prior to screening * ≥40 to \<60 years old * Vaginal pH ≥ 5 * MRS score ≥ 20 * Willing and able to give written informed consent * Willing to consume IP or placebo, complete questionnaires, records, and daily diaries associated with the study and to complete all clinical study visits * Willingness to discontinue consumption of probiotic supplements and food containing added probiotics and/or prebiotics (e.g. yogurts with live, active cultures or supplements) o Note: Screened participants will be eligible to participate after completing a 4-week wash-out period. Exclusion Criteria: * Milk or soy allergy * Women with induced menopause through full or partial hysterectomy, chemotherapy or radiation * Consumption of natural health products used to treat menopausal symptoms such as phytoestrogens, Black Cohosh, dehydroepiandrosterone (DHEA), Dong Quai, vitamin E (\>250 IU/day), high consumption of soy food products, unless a 1-month wash-out period has been completed prior to study commencement * Currently undergoing or have previously undergone HT for treatment of menopausal symptoms, unless a three-month washout has been completed prior to study commencement * Active vaginal infections/abnormalities (e.g. active urinary tract infection (UTI), genital hemorrhage of unknown origin) o Note: Screened participants with infections would be eligible to participate 4 weeks a…