Benefit of Placebo and Different Concentrations of Triamcinolone Acetonide in Nail Psoriasis (NCT03991936) | Clinical Trial Compass
CompletedPhase 4
Benefit of Placebo and Different Concentrations of Triamcinolone Acetonide in Nail Psoriasis
United States11 participantsStarted 2020-03-11
Plain-language summary
This purpose of this study is to determine the lowest effective concentration of intralesional triamcinolone acetonide in the treatment of nail psoriasis.
Who can participate
Age range18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* At least 18 years of age
* Diagnosed with nail psoriasis in at least 2 fingernails
* Willing to give written informed consent and able to adhere to procedures and visit schedules
* Must consent to having the fingernails photographed during the study period
Exclusion Criteria:
* Subject with any clinically significant condition or situation, other than the condition being studied that, in the opinion of the investigator, would interfere with study evaluations or optimal participation in the study. This is including, but not limited to: immunodeficiency, onychomycosis, any other nail condition other than psoriasis, allergy to triamcinolone acetonide, local anesthetic, normal saline, or any other material used for procedures
* Subject who has received radiation therapy, chemotherapy, and/or immunosuppressive drugs within 6 months of study, and/or oral corticosteroids for \>1 month within the 6 months of study (exception: inhaled steroids)
* Subject known to have received treatment with investigational drugs or devices within 30 days prior to enrollment into this study
* Subject who is unwilling to abstain from any cosmetic nail treatments outside those provided by the study clinic, beyond basic nail trimming (i.e. no spa nail treatments, no nail polish use, no other topical prescription nail medication)
* Subject who is unwilling to abstain from any medical nail treatments on their nails other than the study intervention (i.e. topical steroids, anti-fung…
What they're measuring
1
Lowest Effective Concentration of Intralesional Triamcinolone Acetonide for Nail Psoriasis
Timeframe: 24 weeks (end of study)
Trial details
NCT IDNCT03991936
SponsorWeill Medical College of Cornell University