A Pilot Study of Quantitative Tumor Oxygen Measurements in Cervical Cancer

Inclusion Criteria: * Participants must have a biopsy-proven diagnosis of cervical cancer for which interstitial brachytherapy is planned as standard treatment * Age 18 years or older * ECOG performance status of 2 or less (see Appendix A) * Patients who have received prior radiation or chemotherapy may be enrolled on this study * Participant is deemed to be an appropriate candidate for MR-guided brachytherapy by the radiation oncologist and the patient elects to be treated with MR-guided brachytherapy * Participant provides informed consent for prospective collection of relevant medical records for analysis of clinical outcome and treatment-planning techniques * Ability to understand and the willingness to sign a written informed consent document. Participant is willing and able to comply with the protocol for the duration of the study including undergoing treatment and scheduled visits and examinations including follow- up Exclusion Criteria: * Participants who have a contraindication to MRI identified by the MR procedure screening form, such as a pacemaker, aneurysm clip, inner ear implant, neurostimulator, or other non-MR-compatible device or implant * Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements