Prevention and Decolonization of Multidrug-resistant Bacteria With Probiotics

Inclusion Criteria: * CRE- colonized patients * adult patients in hospital (over 18 years old) * Part of the HIBA health care plan * CRE positive rectal swab or stool in the last 14 days Exclusion criteria: * Enteral route enabled (oral, nasogastric tube, gastrostomy or jejunostomy) * Refusal to participate in the study * Not available for weekly checks, minimum up to 12 weeks from enrollment * Clostridium difficile active infection concomitant with CRE swab in a 14-day period days * Neutropenia G3 or greater (less than 1000 neutrophils at the time of enrollment). * Severe immunosuppressed at the time of recruitment according to the CDC definition (patients transplanted, HIV with CD4 \<200, congenital immunodeficiencies, leukemias, lymphomas, cancer disseminated, current chemotherapy or radiotherapy, treatment with corticoids high dose:prednisone 20 mg / d\> 2 weeks or immunosuppressive drugs). * Patient with valvular prostheses * Imminent death * Fistula or dehiscence of the gastrointestinal tract * Acute pancreatitis * Patient of critical units in ileus and / or with high requirement of vasopressors (noradrenaline equal to or greater than 0.5 gammas) at the time of recruitment