Damage Control Surgery in Acute Mesenteric Ischemia (NCT03966430) | Clinical Trial Compass
UnknownNot Applicable
Damage Control Surgery in Acute Mesenteric Ischemia
China60 participantsStarted 2014-01-01
Plain-language summary
Acute mesenteric ischemia (AMI) is a rare but catastrophic abdominal vascular emergency associated with daunting mortality comparable to myocardial infarction or cerebral stroke. Damage control surgery has been extensively used in severe traumatic patients. Very urgent, there was no large-scale in-depth study when extended to a nontrauma setting, especially in the intestinal stroke center. Recently, the liberal use of OA as a damage control surgery adjunct has been proved to improve the clinical outcome in acute superior mesenteric artery occlusion patients. However, there was little information when extended to a prospective study. The purpose of this prospective cohort study was to evaluate whether the application of damage control surgery concept in AMI was related to avoiding postoperative abdominal infection, reduced secondary laparotomy, reduced mortality and improved the clinical outcomes in short bowel syndrome.
Who can participate
Age range
18 Years – 75 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Subjects and their families voluntarily and sign the informed consent form for this trial;
* Age is greater than or equal to 18 years old, less than or equal to 75 years old;
* Patients diagnosed with AMI;
* Subjects can objectively describe the symptoms and follow the follow-up plan.
Exclusion Criteria:
* Those who are judged by the physician to be unfit to participate in the test;
* non-obstructive mesenteric ischemia;
* Aortic dissection complicated with visceral ischemia;
* Intestinal ischemia secondary to other causes (such as volvulus, intestinal adhesion, strangulation);
* There is irreversible heart failure, liver failure or renal failure before diagnosis;
* History of intestinal ischemia surgery or complex abdominal surgery;
* Patients who are unable to perform surgical treatment for injury control or have surgical contraindications for significant injury control;
* Pregnancy, lactating women, subjects with a pregnancy plan within 1 month after the test (including male subjects);
* Participate in other clinical trials within 3 months before the trial;
* Transfer to the hospital within 1 week or discharge automatically;
* Sponsors or researchers or their family members who are directly involved in the trial.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.