Chinese Tuina Therapy for Treatment of Knee Osteoarthritis (NCT03966248) | Clinical Trial Compass
CompletedNot Applicable
Chinese Tuina Therapy for Treatment of Knee Osteoarthritis
China140 participantsStarted 2019-10-19
Plain-language summary
Knee osteoarthritis (KOA) is one of the most common musculoskeletal diseases in clinic. It usually occurs in middle-aged people, especially women. An estimated lifetime risk for KOA is approximately 40% in men and 47% in women. KOA is a chronic disease which can lead to obvious pain, joint stiffness, limitation of activity and even disability, with significant associated costs and effects on society, health systems, and individuals. Tuina therapy has been used and showed effectiveness and safety for pain relief and disability for the patients with musculoskeletal disorders for years in China. Though it is regarded that the Traditional Chinese medicine (TCM) Tuina therapy is similar to the modern manual therapies, the modalities of TCM tuina therapy are different and effect maybe equal to or more better than the modern manual therapy in clinic. However, little evidence exists that Tuina benefits the KOA. The investigators will do this in a randomized, parallel, active controlled study to observe whether TCM Tuina is more beneficial to KOA than the physical manual therapy, which has been considered an effective and standard care for KOA.
Who can participate
Age range40 Years – 75 Years
SexALL
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Inclusion criteria
✓. Diagnosis of KOA;
✓. Age 40-75 years;
✓. KL (Kellgren-Lawrence) grade Ⅱ or Ⅲ in recent 3 months;
✓. NRS score of pain at least more than 4 points;
✓. Single/bilateral knee pain, duration of more than 6 month; If the patient has KOA on both legs, the heavier leg is selected for study.
Exclusion criteria
✕. Surgery history of knee or waiting for surgery (knee replacement or knee arthroscopy);
✕. Knee pain caused by other diseases (such as joint bodies, severe effusion of joint cavity, infection, malignant tumors, autoimmune diseases, trauma, etc.);
✕. Oral administration of hormones within 3 month, intra-articular injection within 6 months, knee injuries or open injuries within 6 months, or knee arthroscopy within 1 year.
✕. Severe acute/chronic organic or mental diseases;
What they're measuring
1
Change in Western Ontario and McMaster University Osteoarthritis Index (WOMAC)