Nasal High Flow Therapy in Surgical Patients with Unrecognized Obstructive Sleep Apnea (NCT03964376) | Clinical Trial Compass
CompletedNot Applicable
Nasal High Flow Therapy in Surgical Patients with Unrecognized Obstructive Sleep Apnea
Canada, Hong Kong, Malaysia22 participantsStarted 2019-10-01
Plain-language summary
In this study the investigators will determine whether using high flow oxygen in moderate-to-severe Obstructive Sleep Apnea patients following a major non cardiac surgery is more efficacious than usual care in preventing decrease in oxygen level in blood.
Who can participate
Age range45 Years
SexALL
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Inclusion Criteria:
* Adult, age ≥45 years, undergoing major elective non cardiac surgery under general and/or regional anesthesia with anticipated overnight stay or longer in hospital
* Patients with untreated moderate-to-severe Obstructive Sleep Apnea.
* STOP-Bang score 5 or higher
Exclusion Criteria:
* Predetermined need for postoperative CPAP therapy or ventilation,
* Cheyne-Stokes respiration or Central Apnea,
* Oxygen dependent due to moderate to severe chronic obstructive lung disease available Forced Expiratory Volume at 1 second of \< 50% predicted) or advanced interstitial lung disease,
* Pre-existing chronic hypercapnia or obesity hypoventilation syndrome, Intracranial and otolaryngological procedures, and
* Unable to use nasal high-flow (nasal/oral malformations, pre-existing tracheostomy, planned postoperative nasal packing).