The primary objectives of this study are: * To describe the safety profile of each of the investigational vaccine formulations for all participants * To describe the humoral and cell-mediated immune responses to all of the investigational vaccine formulations * To evaluate the dose response to vaccine components * To describe the magnitude, quality, and longevity of immune responses to each of the investigational vaccine formulations
Age range
19 Years – 21 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Number of participants reporting immediate adverse events (AEs)
Timeframe: Within 30 minutes post-vaccination
Number of participants reporting solicited injection sites or systemic reactions
Timeframe: Within 7 days post-vaccination
Number of participants reporting unsolicited AEs
Timeframe: Within 30 days post-vaccination
Number of participants reporting serious adverse events (SAEs)
Timeframe: Up to 12 months post-vaccination
Number of participants reporting medically attended adverse events (MAAEs)
Timeframe: Up to 12 months post-vaccination
Number of participants reporting adverse events of special interest (AESIs)
Timeframe: Up to 12 months post-vaccination
Number of participants reporting Grade 2 and Grade 3 laboratory parameter abnormalities
Timeframe: Within 60 days post-vaccination
Geometric mean concentrations (GMCs) of anti-pertussis antigen immunoglobulins
Timeframe: From Day 0 to Day 360
GMCs of anti-diphtheria toxoid immunoglobulins
Timeframe: From Day 0 to Day 360
GMCs of anti-tetanus toxoid immunoglobulins
Timeframe: From Day 0 to Day 360
Geometric means of antigen-specific cells
Timeframe: From Day 0 to Day 360
Percentages of antigen-specific cells
Timeframe: From Day 0 to Day 360