Improving Bowel Function and Quality of Life After Spinal Cord Injury

Inclusion Criteria: * At least 18 years of age at the time of enrollment * At least 2 years post injury * Non-progressive spinal cord injury * Stable medical condition * Unable to voluntarily move all joints of the legs * Unable to stand independently * Cardiovascular dysfunction including presence of persistent resting low blood pressures and/or symptoms of autonomic dysreflexia and/or orthostatic hypotension and/or dysregulation in response to postural changes and/or highly variable blood pressures in 24 hour period * Bowel dysfunction as a result of spinal cord injury Exclusion Criteria: * Ventilator dependent * Untreated painful musculoskeletal dysfunction, unhealed fracture or pressure sore * Untreated psychiatric disorder or ongoing drug abuse * Colostomy bag * Any implanted pump (i.e., baclofen pump, pain pump, etc) * Cardiovascular or bowel dysfunction unrelated to SCI * Ongoing nicotine use * Pregnant at the time of enrollment or planning to become pregnant during the time course of the study