Acute Decompensation of Pulmonary Hypertension (NCT03926572) | Clinical Trial Compass
CompletedNot Applicable
Acute Decompensation of Pulmonary Hypertension
France145 participantsStarted 2019-09-19
Plain-language summary
The main objective of this study is to analyze the survival of a cohort of patients admitted for acute decompensation of pulmonary arterial hypertension or postembolic pulmonary hypertension and to establish the prognostic value of biomarkers.
Who can participate
Age range18 Years
SexALL
See this in plain English?
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Inclusion Criteria:
* Adult patients over 18 years
* Diagnosis of Pulmonary arterial hypertension or non-operable chronic thromboembolic pulmonary hypertension established by right cardiac catheterization prior to inclusion in the study
* Patients admitted in intensive care unit for acute decompensation of pulmonary hypertension requiring intravenous diuretic therapy ± use of inotropes or vasopressors.
* Patients must have given their written informed consent to participate in the study after having received adequate previous information and prior to any study-specific procedures
Exclusion Criteria:
* Patients with post-capillary pulmonary hypertension
* Patients with pulmonary hypertension associated with chronic respiratory disease
* Patients with pulmonary hypertension with unclear/or multifactorial mechanisms
* Patients with operable chronic thromboembolic pulmonary hypertension
* Shock due to another cause than acute decompensation of pulmonary hypertension
* Pregnant women, or breast feeding women
* Adult protected person
* Person deprived of liberty
* Person admitted without consent
* Pregnant or breastfeeding women
What they're measuring
1
time to death, circulatory assistance or emergency transplantation within 90 days following admission to intensive care unit