Analysis of the Nasal Mucosal Immune Response in HIV Infection

Inclusion Criteria: * Chronic HIV-1 infected subjects followed in Department of Internal Medicine and Clinical Immunology in Bicetre Hospital * Healthy male or female aged between 20 and 69 (included) years * Whatever the clinical status and the lymphocytes T CD4+ * Patients treatment-naive or under ARV treatment whatever the molecules * 3 groups of patients, according to their HIV1 viral loads * Virémic : viral load \> 500 copies/mL, treatment-naive or treated (failing) regardless of the cause of persistent viremic * No Viremic : \< 50 copies/ml under treatment at least from 12 months * Spontaneous Controllers from the Codex Cohort (Controllers cohort from ANRS) or not with the following inclusion criteria Chronic HIV-1 infected subjects since 5 years, asymptomatic With 5 last viral loads \< 400 copies /mL Whatever the lymphocytes T CD4 rates Naive of treatment except transient treatment for prevention of mother-to-child transmission * Subject considered to be free on the day of study of an acute condition or infection that may interfere with the results of the study, based on the clinical examination performed by the investigator * Caucasian and Sub Saharan patients -18,5 ≤ BMI ≤ 32 kg/m² * Subjects who, according to the investigator, can and will comply with the requirements of the protocol and are available for the scheduled visit at the investigational site. Ability to give their informed consent in writing * Affiliated to the French social security or assimilate…