CompletedNot Applicable

Energy Metabolism in Branched-chain Organic Acidemias

Germany57 participantsStarted 2012-03

Plain-language summary

Energy metabolism and insulin sensitivity were assessed in a case-control study in patients with branched-chain organic acidemias.

Who can participate

Age range5 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * known branched-chain organic acidemia diagnosed by enzymatic or genetic test * age\>5 years Exclusion Criteria: * acute inflammatory conditions with fever, cold symptoms, gastro-intestinal infection within the last 24 hours * contraindications for an oral glucose tolerance test such as fasting blood glucose \>126 mg/dl, severe chronic gastrointestinal conditions, allergy against black currant * contraindications for magnetic resonance tomography (MRT) such as claustrophobia, metallic implants which are not MRT compatible

What they're measuring

Hepatic and skeletal muscle energy metabolism

Timeframe: At baseline

Trial details

NCT IDNCT03917212

SponsorGerman Diabetes Center

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2017-11

View on ClinicalTrials.gov More Energy Metabolism trials