Effect of Erenumab-aooe on Disability and Work Productivity in Employed Subjects With Episodic Migraine

Inclusion Criteria: * Greater than or equal to 18 years of age upon entry into screening. * Documented history of migraine with or without aura according to the IHS ICHD-III for greater than or equal to 12 months * Has EM defined as history of greater than or equal to 4 and less than 15 migraine days and less than 15 headache days per month on average during the 3 months prior to initial screening * Employed greater than or equal to 20 hours/week upon entry into initial screening, stable for at least 3 months in the same job and has not specified willful termination of employment throughout the duration of the study. Employment is defined by work outside the home, self-employed, or works from home * Has greater than or equal to 4 hours of lost productive time due to headache/migraine and/or related symptoms in the past month prior to initial screening as determined by subject * Has total disability score of greater than 10 as assessed by MIDAS (3-month recall) at initial screening * History of treatment failure with at least 1 preventive treatment category for migraine Exclusion Criteria: * Older than 50 years of age at migraine onset * History of cluster headache, hemiplegic migraine, or other trigeminal autonomic cephalalgia. * Taken an opioid and/or opioid-containing analgesic greater than or equal to 4 days during the 1 month prior to screening for any indication * Taken a butalbital and/or butalbital-containing analgesic greater than or equal to 4 days during the 1 mo…